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researcher, Dipanjan Pan, an assistant professor of bioengineering with the University of Illinois at Urbana-Champaign. The experiments being conducted on a recent day were not only just a few of the many the team will need to run before testing their blood substitute in people, but were also early steps to show that their design, with any luck, can steer. Lab tests involving mice and rats have proven that the artificial red blood cells can effectively deliver oxygen to needy tissues, the researchers reported. Dont expect it to be available anytime soon though, Doctor warned. If its successful, ErythroMer could be freeze-dried into a powder and stored safely for years, so that when its needed, it can be mixed with sterile water and administered. Researchers have created an artificial red blood cell that effectively picks up oxygen in the lungs and delivers it to tissues throughout the body. However, the artificial red blood cells will never totally replace the real thing, Doctor said. The product also could be useful in rural areas or areas where traumatic events occur and blood products arent readily available. The.K.s National Health Service announced plans on June 25 for a small safety trial of 20 people that will begin in 2017. .
There has been about 50, 60 years of research in trying to make a blood substitute that has not worked, said Doctor, a pediatric critical care physician and researcher at Washington University. Additionally, about 20,000 trauma deaths in the United States occur each year due to blood loss prior to arriving at a treatment center. And when someone loses a lot of blood and goes into shock, their blood vessels only become more leaky, Scott said.
There also was an unintended reaction between naked hemoglobin and nitric oxide, a substance released by the lining of blood vessels that allows the vessels to relax and open up, Doctor noted. Findings from the study are scheduled to be presented Saturday at the American Society of Hematologys annual meeting, in San Diego.
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Baxter, Northfield Laboratories, and Biopure abandoning their attempts. About the Author Tags. One advantage of the small size of the substitute blood, both Scott and Doctor said, is that it could be used for people with sickle cell disease. Alan Mast, a senior investigator with the BloodCenter of Wisconsins Blood Research Institute. In an email, an FDA spokeswoman said that studies on these types of products have found principles of war they are not safe or effective, but that the agency recognizes they potentially could be lifesaving in situations where blood transfusion is necessary, but blood is not available. The team has formed a company called KaloCyte (Greek for good cell) to make the substitute for further studies.
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